The resume is just a preview. The interview is the show..gif)
I have participated in a quite a few interviews in the past couple of years, and I have learned from doing. I no longer feel ridiculously nervous in face-to-face interviews with hiring managers. I just acknowledge them as another human being in the room. The worst thing they can do is not invite me to join their team. It is not the end of the world. I know the right opportunity will come my way regardless. It takes a balance of confidence and comfort to walk into an interview with this attitude.
However, you never want to come off too confident or too comfortable. Your resume has sparked the HR managers attention and they apparently see something on that piece of paper that interests them. You should be comfortable in your abilities and past experiences, and therefore be comfortable in your delivery. It is important to be relaxed and cool in the interview. You want to convey your interest in the position to the HR rep, but you do not ever want to seem over eager. Balance is essential.
Know your stuff. Most of the interview is going to be focused on you. All of the interviews I have participated in since being in college have been structured around behavioral or situational experiences. For example, I was recently asked in an interview, describe a situation in which you did not complete an assignment at the assigned deadline. This question was a breeze because I immediately thought of an incident that complimented my qualities. Aside from being on-point about yourself, be well-informed about the company you are interviewing with. Take the time to research what the company does, how it does it, and how successful it is in efforts.
Lastly, know that you are in control. Own the interview.